Honors Theses

Date of Award

5-2024

Document Type

Undergraduate Thesis

Degree Name

BS

Department

Chemistry

Faculty Mentor

David Forbes

Advisor(s)

Christy Wheeler West, Kevin West

Abstract

Our research focuses on a cost-effective approach which minimizes synthetic overhead when assembling compounds with diazirine functionality. The goals are to prevent the surplus use of ammonia in the formation of diaziridine functionality and use an IKA Electrosyn 2.0 in the oxidation of diaziridine functionality. Success with either specific aim will significantly reduce the synthetic overhead currently observed. Diazirine functionality plays a vital role in a vast number of applications. Two of interest to us include diazirine functionality as a next generation propellant and as a photoaffinity label. With the latter, this strategy plays a vital role in drug discovery and biomedical research as it allows researchers to study, understand, manipulate, and control complex biological systems. Moreover, previous research has shown that diazirine functionality has the potential to be used as propellants, so this project also aims to explore the energetic properties of this functionality and develop a deeper understanding of their physical properties. The energetic properties are assessed using digital scanning calorimetry and thermogravimetric analysis.

Comments

© 2024 Abby Mock ALL RIGHTS RESERVED

Additional Files
Mock_Abby_Poster.pdf (1253 kB)
Download

Share

COinS