Digitized Honors Theses (2002-2017)

Date of Award

5-2015

Document Type

Undergraduate Thesis

Degree Name

BS

Department

Biomedical Sciences

Faculty Mentor

Silas Leavesley, Ph.D

Advisor(s)

Thomas Grant Glover, Ph.D, Thomas Rich, Ph.D

Abstract

Colorectal cancer is among the most common cancers in American men and women. The key challenge in cancer control and elimination is early detection. Endoscopic technologies enable internal organ screening for diagnostic purposes. While light endoscopy is currently used for the detection and identification of lesions of gastrointestinal tract and upper airways. We have proposed that hyperspectral imaging can be used to improve detection, sensitivity, and specificity, leading to reduced miss-rates in cancer detection. To enable real time hyperspectral imaging endoscopy, we have designed a hyperspectral light source that uses illumination bands produced by light emitting diodes. The illumination bands are regulated and combined via electronic control boards and a novel light pipe configuration. The hyperspectral endoscope system involved electrical, optical, mechanical, and software subsystems. The specific goal of my work was to design the electrical subsystem which involved a driver board, LED board, and peripheral electronic components o enable control of illumination bands. The optical subsystem involved LEDs and a light pipe for light wavelength combination. The mechanical subsystem involved design of L-brace and mounting brace to secure optical alignment, and the software subsystem enables digital and analog control of the electronic components. All subsystems of the hyperspectral light source were successfully designed, produced and connected. The hardware was designed to allow for rack mounting for easy mobility. The hyperspectral imaging endoscope light source will be tested after connection of the subsystems is completed.

Comments

© 2015 Aniebiet Udoh, ALL RIGHTS RESERVED

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