Title
Unpacking the intricacies of Rickettsia-vector interactions
Document Type
Article
Publication Title
Trends in parasitology
Abstract
Although Rickettsia species are molecularly detected among a wide range of arthropods, vector competence becomes an imperative aspect of understanding the ecoepidemiology of these vector-borne diseases. The synergy between vector homeostasis and rickettsial invasion, replication, and release initiated within hours (insects) and days (ticks) permits successful transmission of rickettsiae. Uncovering the molecular interplay between rickettsiae and their vectors necessitates examining the multifaceted nature of rickettsial virulence and vector infection tolerance. Here, we highlight the biological differences between tick- and insect-borne rickettsiae and the factors facilitating the incidence of rickettsioses. Untangling the complex relationship between rickettsial genetics, vector biology, and microbial interactions is crucial in understanding the intricate association between rickettsiae and their vectors.
First Page
734
Last Page
746
DOI
10.1016/j.pt.2021.05.008
Publication Date
8-1-2021
Recommended Citation
Laukaitis, Hanna J. and Macaluso, Kevin R., "Unpacking the intricacies of Rickettsia-vector interactions" (2021). Department of Microbiology and Immunology Faculty and Staff Publications and Presentations. 8.
https://jagworks.southalabama.edu/med_microbio_immunology_faculty_staff_pubs/8